Comorbilidades infecciosas en la gravedad y mortalidad por Covid-19: análisis del aporte científico en The Lancet Publishing Group

Jesús César Sandoval Trigos, Michael Raiser Vásquez Ramírez, Kathy Lesslie Javier Palacios, Jefrin Marlon Silva Murillo

Resumen


El número de casos totales de la enfermedad coronavirus-2019 (COVID-19) sigue aumentando rápidamente, amenazando a miles o millones de personas con condiciones crónicas preexistentes que se ven afectados de manera desproporcionada. Hasta el 2020,  el centro de recursos de coronavirus de la Universidad Johns Hopkins informó que en todo el mundo más de 180 países han sido afectados con COVID-19 con más de doce millones de casos confirmados y más de 500.000 muertes. A medida que continúa la investigación relacionada con los posibles factores de riesgo de mortalidad por COVID-19, se hace evidente que las personas con comorbilidades subyacentes, como enfermedades cardiovasculares, hipertensión, diabetes, insuficiencia cardíaca congestiva, enfermedad cerebrovascular, enfermedad renal crónica, enfermedad hepática crónica, cáncer, enfermedad pulmonar obstructiva crónica, el asma y el VIH/SIDA pueden tener un mayor riesgo de muerte por COVID-19.  El objetivo de este trabajo es determinar las comorbilidades infecciosas en la gravedad y mortalidad por Covid-19 especialmente asociadas con VIH/SIDA y tubercolosis, respodiendo a la siguiente pregunta: ¿La comunidad científica mundial se ha preocupado por la comorbilidad infecciosa en casos de covid-19 severo y fatales?. Un análisis hecho al grupo de referencias The Lancet Publishing Group fue realizado para dar repuesta a dicha pregunta.


Palabras clave


Covid-19, VIH, Tuberculosos, comorbilidad, mortalidad

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Referencias


Achan, J., Serwanga, A., Wanzira, H., Kyagulanyi, T., Nuwa, A., Magumba, G., Kusasira, S., Sewanyana, I., Tetteh, K., Drakeley, C., Nakwagala, F., Aanyu, H., Opigo, J., Hamade, P., Marasciulo, M., Baterana, B., & Tibenderana, J. K. (2022). Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort study in Uganda. The Lancet. Microbe, 3(1), e62–e71. https://doi.org/10.1016/S2666-5247(21)00240-8

Ambrosioni, J., Blanco, J. L., Reyes-Urueña, J. M., Davies, M. A., Sued, O., Marcos, M. A., Martínez, E., Bertagnolio, S., Alcamí, J., Miro, J. M., & COVID-19 in HIV Investigators (2021). Overview of SARS-CoV-2 infection in adults living with HIV. The lancet. HIV, 8(5), e294–e305. https://doi.org/10.1016/S2352-3018(21)00070-9

Arceo-Gomez, E. O., Campos-Vazquez, R. M., Esquivel, G., Alcaraz, E., Martinez, L. A., & Lopez, N. G. (2022). The income gradient in COVID-19 mortality and hospitalisation: An observational study with social security administrative records in Mexico. Lancet regional health. Americas, 6, 100115. https://doi.org/10.1016/j.lana.2021.100115

Bertagnolio, S., Thwin, S. S., Silva, R., Nagarajan, S., Jassat, W., Fowler, R., Haniffa, R., Reveiz, L., Ford, N., Doherty, M., & Diaz, J. (2022). Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19. The lancet. HIV, 9(7), e486–e495. https://doi.org/10.1016/S2352-3018(22)00097-2

Bhaskaran, K., Rentsch, C. T., MacKenna, B., Schultze, A., Mehrkar, A., Bates, C. J., Eggo, R. M., Morton, C. E., Bacon, S. C. J., Inglesby, P., Douglas, I. J., Walker, A. J., McDonald, H. I., Cockburn, J., Williamson, E. J., Evans, D., Forbes, H. J., Curtis, H. J., Hulme, W. J., Parry, J., & Goldacre, B. (2021). HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. The lancet. HIV, 8(1), e24–e32. https://doi.org/10.1016/S2352-3018(20)30305-2

Boulle, A., Davies, MA., Hussey, H., Ismail, M., Morden, E., &Vundle, Z. (2020) Risk factors for coronavirus disease 2019 (COVID-19) death in a population cohort study from the Western Cape Province, South Africa. Clinical Infectious Diseases 73, e2005–e2015. https://doi.org/10.1093/cid/ciaa1198

Cabello, A., Zamarro, B., Nistal, S., Victor, V., Hernández, J., Prieto-Pérez, L., Carrillo, I., Álvarez, B., Fernández-Roblas, R., Hernández-Segurado, M. (2021). COVID-19 in people living with HIV: A multicenter case-series study. International Journal of Infectious Diseases, (102), 310-315. https://doi.org/10.1016/j.ijid.2020.10.060

Chen, T., Wu, D., Chen, H., Yan, W., Yang, D., Chen, G., Ma, K., Xu, D., Yu, H., Wang, H., Wang, T., Guo, W., Chen, J., Ding, C., Zhang, X., Huang, J., Han, M., Li, S., Luo, X., Zhao, J., & Ning, Q. (2020). Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ (Clinical research ed.), 368, m1091. https://doi.org/10.1136/bmj.m1091

Cilloni, L., Fu, H., Vesga, J. F., Dowdy, D., Pretorius, C., Ahmedov, S., Nair, S. A., Mosneaga, A., Masini, E., Sahu, S., & Arinaminpathy, N. (2020). The potential impact of the COVID-19 pandemic on the tuberculosis epidemic a modelling analysis. EClinicalMedicine, 28, 100603. https://doi.org/10.1016/j.eclinm.2020.100603

Clark, A., Jit, M., Warren-Gash, C., Guthrie, B., Wang, H. H. X., Mercer, S. W., Sanderson, C., McKee, M., Troeger, C., Ong, K. L., Checchi, F., Perel, P., Joseph, S., Gibbs, H. P., Banerjee, A., Eggo, R. M., & Centre for the Mathematical Modelling of Infectious Diseases COVID-19 working group (2020). Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study. The Lancet. Global health, 8(8), e1003–e1017. https://doi.org/10.1016/S2214-109X(20)30264-3

Danser, A. H. J., Epstein, M., & Batlle, D. (2020). Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers. Hypertension (Dallas, Tex. : 1979), 75(6), 1382–1385. https://doi.org/10.1161/HYPERTENSIONAHA.120.15082

Dryden, M., Mudara, C., Vika, C., Blumberg, L., Mayet, N., Cohen, C., Tempia, S., Parker, A., Nel, J., Perumal, R., Groome, M. J., Conradie, F., Ndjeka, N., Sigfrid, L., Merson, L., & Jassat, W. (2022). Post-COVID-19 condition 3 months after hospitalisation with SARS-CoV-2 in South Africa: a prospective cohort study. The Lancet. Global health, 10(9), e1247–e1256. https://doi.org/10.1016/S2214-109X(22)00286-8

Guan, W. J., Ni, Z. Y., Hu, Y., Liang, W. H., Ou, C. Q., He, J. X., Liu, L., Shan, H., Lei, C. L., Hui, D. S. C., Du, B., Li, L. J., Zeng, G., Yuen, K. Y., Chen, R. C., Tang, C. L., Wang, T., Chen, P. Y., Xiang, J., Li, S. Y., & China Medical Treatment Expert Group for Covid-19 (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. The New England journal of medicine, 382(18), 1708–1720. https://doi.org/10.1056/NEJMoa2002032

Guo, W., Ming, F., & Dong, Y. (2020). A Survey for COVID-19 among HIV/AIDS Patients in Two Districts of Wuhan, China. Preprint research paper, The Lancet. http://dx.doi.org/10.2139/ssrn.3550029

Hadi, Y. B., Naqvi, S. F. Z., Kupec, J. T., & Sarwari, A. R. (2020). Characteristics and outcomes of COVID-19 in patients with HIV: a multicentre research network study. AIDS (London, England), 34(13), F3–F8. https://doi.org/10.1097/QAD.0000000000002666

Hamming, I., Timens, W., Bulthuis, M., Lely, A., Navis, G. & van Goor, H. (2004) Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland. 203 (2), 631–7. https://doi.org/10.1002/path.1570

Hatmi, Z.N. (2021) A Systematic Review of Systematic Reviews on the COVID-19 Pandemic. SN Compr. Clin. Med., 3, 419–436. https://doi.org/10.1007/s42399-021-00749-y

Heskin, J., Pallett, S. J. C., Mughal, N., Davies, G. W., Moore, L. S. P., Rayment, M., & Jones, R. (2022). Caution required with use of ritonavir-boosted PF-07321332 in COVID-19 management. Lancet (London, England), 399(10319), 21–22. https://doi.org/10.1016/S0140-6736(21)02657-X

Hogan, A. B., Jewell, B. L., Sherrard-Smith, E., Vesga, J. F., Watson, O. J., Whittaker, C., Hamlet, A., Smith, J. A., Winskill, P., Verity, R., Baguelin, M., Lees, J. A., Whittles, L. K., Ainslie, K. E. C., Bhatt, S., Boonyasiri, A., Brazeau, N. F., Cattarino, L., Cooper, L. V., Coupland, H., & Hallett, T. B. (2020). Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study. The Lancet. Global health, 8(9), e1132–e1141. https://doi.org/10.1016/S2214-109X(20)30288-6

Huang, J., Xie, N., Hu, X., Yan, H., Ding, J., &Liu, P.(2020). Epidemiological, virological and serological features of COVID-19 cases in people living with HIV in Wuhan City: A population-based cohort study. Clinical Infectious Diseaseshttps://doi.org/10.1093/cid/ciaa1186

Izcovich, A., Ragusa, M. A., Tortosa, F., Marzio, M. A. L., Agnoletti, C., Bengolea, A., Ceirano, A., Espinosa, F., Saavedra, E., Sanguine, V., Tassara, A., Cid, C., Catalano, H. N., Agarwal, A., Foroutan, F., & Rada, G. (2022). Correction: Prognostic factors for severity and mortality in patients infected with COVID-19: A systematic review. PloS one, 17(5), e0269291. https://doi.org/10.1371/journal.pone.0269291

Jassat, W., Cohen, C., Tempia, S., Masha, M., Goldstein, S., Kufa, T., Murangandi, P., Savulescu, D., Walaza, S., Bam, J. L., Davies, M. A., Prozesky, H. W., Naude, J., Mnguni, A. T., Lawrence, C. A., Mathema, H. T., Zamparini, J., Black, J., Mehta, R., Parker, A., & DATCOV author group (2021). Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study. The lancet. HIV, 8(9), e554–e567. https://doi.org/10.1016/S2352-3018(21)00151-X

Johns Hopkins University. (2020). Coronavirus Resource Center 2020. Disponible en: https://coronavirus.jhu.edu/ (Acceso agosto 2022).

Wai, A. K., Chan, C. Y., Cheung, A. W., Wang, K., Chan, S. C., Lee, T. T., Luk, L. Y., Yip, E. T., Ho, J. W., Tsui, O. W., Cheung, K. W., Lee, S., Tong, C. K., Yamamoto, T., Rainer, T. H., & Wong, E. L. (2022). Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among high-risk patients with mild to moderate COVID-19. The Lancet regional health. Western Pacific, 30, 100602. https://doi.org/10.1016/j.lanwpc.2022.100602

Kinner, S. A., Young, J. T., Snow, K., Southalan, L., Lopez-Acuña, D., Ferreira-Borges, C., & O'Moore, É. (2020). Prisons and custodial settings are part of a comprehensive response to COVID-19. The Lancet. Public health, 5(4), e188–e189. https://doi.org/10.1016/S2468-2667(20)30058-X

Madhi, S. & Nel, J. (2021). Epidemiology of severe COVID-19 from South Africa. The Lancet HIV. 8(9), E524-E526. https://doi.org/10.1016/S2352-3018(21)00183-1

Maza-Arnedo, F., Paternina-Caicedo, A., Sosa, C. G., de Mucio, B., Rojas-Suarez, J., Say, L., Cresswell, J. A., de Francisco, L. A., Serruya, S., Lic, D. C. F. P., Urbina, L., Hilaire, E. S., Munayco, C. V., Gil, F., Rousselin, E., Contreras, L., Stefan, A., Becerra, A. V., Degraff, E., Espada, F., & Colomar, M. (2022). Maternal mortality linked to COVID-19 in Latin America: Results from a multi-country collaborative database of 447 deaths. Lancet regional health. Americas, 12, 100269. https://doi.org/10.1016/j.lana.2022.100269

Migliori, G. B., Thong, P. M., Akkerman, O., Alffenaar, J. W., Álvarez-Navascués, F., Assao-Neino, M. M., Bernard, P. V., Biala, J. S., Blanc, F. X., Bogorodskaya, E. M., Borisov, S., Buonsenso, D., Calnan, M., Castellotti, P. F., Centis, R., Chakaya, J. M., Cho, J. G., Codecasa, L. R., D'Ambrosio, L., Denholm, J., & Goletti, D. (2020). Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services, January-April 2020. Emerging infectious diseases, 26(11), 2709–2712. https://doi.org/10.3201/eid2611.203163

Mndala, L., Monk, E. J. M., Phiri, D., Riches, J., Makuluni, R., Gadama, L., Kachale, F., Bilesi, R., Mbewe, M., Likaka, A., Chapuma, C., Kumwenda, M., Maseko, B., Ndamala, C., Kuyere, A., Munthali, L., Henrion, M. Y. R., Masesa, C., & Lissauer, D. (2022). Comparison of maternal and neonatal outcomes of COVID-19 before and after SARS-CoV-2 omicron emergence in maternity facilities in Malawi (MATSurvey): data from a national maternal surveillance platform. The Lancet. Global health, 10(11), e1623–e1631. https://doi.org/10.1016/S2214-109X(22)00359-X

Motta, I., Centis, R., D'Ambrosio, L., García-García, J. M., Goletti, D., Gualano, G., Lipani, F., Palmieri, F., Sánchez-Montalvá, A., Pontali, E., Sotgiu, G., Spanevello, A., Stochino, C., Tabernero, E., Tadolini, M., van den Boom, M., Villa, S., Visca, D., & Migliori, G. B. (2020). Tuberculosis, COVID-19 and migrants: Preliminary analysis of deaths occurring in 69 patients from two cohorts. Pulmonology, 26(4), 233–240. https://doi.org/10.1016/j.pulmoe.2020.05.002

Nomah, D. K., Reyes-Urueña, J., Díaz, Y., Moreno, S., Aceiton, J., Bruguera, A., Vivanco-Hidalgo, R. M., Llibre, J. M., Domingo, P., Falcó, V., Imaz, A., Cortés, C., Force, L., Letang, E., Vilaró, I., Casabona, J., Miro, J. M., & PISCIS study group (2021). Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study. The lancet. HIV, 8(11), e701–e710. https://doi.org/10.1016/S2352-3018(21)00240-X

OPS. (2020). Tuberculosis y COVID-19: lo que el personal de salud y las autoridades deben saber detalles. Disponible en; https://www3.paho.org/hq/index.php?option=com_content&view=article&id=15759:tuberculosis-and-covid-19-what-health-workers-and-authorities-need-to-know&Itemid=0〈=es#gsc.tab=0 (Acceso agosto 2022)

Ozonoff, A., Schaenman, J., Jayavelu, N. D., Milliren, C. E., Calfee, C. S., Cairns, C. B., Kraft, M., Baden, L. R., Shaw, A. C., Krammer, F., van Bakel, H., Esserman, D. A., Liu, S., Sesma, A. F., Simon, V., Hafler, D. A., Montgomery, R. R., Kleinstein, S. H., Levy, O., Bime, C., & IMPACC study group members (2022). Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study. EBioMedicine, 83, 104208. https://doi.org/10.1016/j.ebiom.2022.104208

Petrone, L., Petruccioli, E., Vanini, V., Cuzzi, G., Gualano, G., Vittozzi, P., Nicastri, E., Maffongelli, G., Grifoni, A., Sette, A., Ippolito, G., Migliori, G. B., Palmieri, F., & Goletti, D. (2021). Coinfection of tuberculosis and COVID-19 limits the ability to in vitro respond to SARS-CoV-2. International journal of infectious diseases, 113 Suppl 1, S82–S87. https://doi.org/10.1016/j.ijid.2021.02.090

RECOVERY Collaborative Group. (2020). Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet (London, England), 396(10259), 1345–1352. https://doi.org/10.1016/S0140-6736(20)32013-4

RECOVERY Collaborative Group (2022). Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. Lancet (London, England), 400(10349), 359–368. https://doi.org/10.1016/S0140-6736(22)01109-6

Shi, S., Qin, M., Shen, B., Cai, Y., Liu, T., Yang, F., Gong, W., Liu, X., Liang, J., Zhao, Q., Huang, H., Yang, B., & Huang, C. (2020). Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA cardiology, 5(7), 802–810. https://doi.org/10.1001/jamacardio.2020.0950

Song, W. M., Zhao, J. Y., Zhang, Q. Y., Liu, S. Q., Zhu, X. H., An, Q. Q., Xu, T. T., Li, S. J., Liu, J. Y., Tao, N. N., Liu, Y., Li, Y. F., & Li, H. C. (2021). COVID-19 and Tuberculosis Coinfection: An Overview of Case Reports/Case Series and Meta-Analysis. Frontiers in medicine, 8, 657006. https://doi.org/10.3389/fmed.2021.657006

Sy, K. T. L., Haw, N. J. L., & Uy, J. (2020). Previous and active tuberculosis increases risk of death and prolongs recovery in patients with COVID-19. Infectious diseases (London, England), 52(12), 902–907. https://doi.org/10.1080/23744235.2020.1806353

Tadolini, M., Codecasa, L. R., García-García, J. M., Blanc, F. X., Borisov, S., Alffenaar, J. W., Andréjak, C., Bachez, P., Bart, P. A., Belilovski, E., Cardoso-Landivar, J., Centis, R., D'Ambrosio, L., Luiza De Souza-Galvão, M., Dominguez-Castellano, A., Dourmane, S., Fréchet Jachym, M., Froissart, A., Giacomet, V., Goletti, D., & Migliori, G. B. (2020). Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases. The European respiratory journal, 56(1), 2001398. https://doi.org/10.1183/13993003.01398-2020

Visca, D., Ong, C. W. M., Tiberi, S., Centis, R., D'Ambrosio, L., Chen, B., Mueller, J., Mueller, P., Duarte, R., Dalcolmo, M., Sotgiu, G., Migliori, G. B., & Goletti, D. (2021). Tuberculosis and COVID-19 interaction: A review of biological, clinical and public health effects. Pulmonology, 27(2), 151–165. https://doi.org/10.1016/j.pulmoe.2020.12.012

Vizcarra, P., Pérez-Elías, M. J., Quereda, C., Moreno, A., Vivancos, M. J., Dronda, F., Casado, J. L., & COVID-19 ID Team (2020). Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort. The lancet. HIV, 7(8), e554–e564. https://doi.org/10.1016/S2352-3018(20)30164-8

Wang, J., Xu, C., Wong, Y. K., He, Y., Adegnika, A. A., Kremsner, P. G., Agnandji, S. T., Sall, A. A., Liang, Z., Qiu, C., Liao, F. L., Jiang, T., Krishna, S., & Tu, Y. (2020). Preparedness is essential for malaria-endemic regions during the COVID-19 pandemic. Lancet (London, England), 395(10230), 1094–1096. https://doi.org/10.1016/S0140-6736(20)30561-4

WHO. (2021). Global Tuberculosis Report 2021. Geneva, WHO, 2021. Disponible en: https://www.who.int/publications-detail-redirect/9789240037021(Acceso agosto 2022).

Xu, X. W., Wu, X. X., Jiang, X. G., Xu, K. J., Ying, L. J., Ma, C. L., Li, S. B., Wang, H. Y., Zhang, S., Gao, H. N., Sheng, J. F., Cai, H. L., Qiu, Y. Q., & Li, L. J. (2020). Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ (Clinical research ed.), 368, m606. https://doi.org/10.1136/bmj.m606

Xu, Z., Zhang, C. & Wang, FS. (2020). COVID-19 in people with HIV. The Lancet HIV,7(8) E524-E526. https://doi.org/10.1016/S2352-3018(20)30163-6

Yang, X., Sun, J., Patel, R. C., Zhang, J., Guo, S., Zheng, Q., Olex, A. L., Olatosi, B., Weissman, S. B., Islam, J. Y., Chute, C. G., Haendel, M., Kirk, G. D., Li, X., & National COVID Cohort Collaborative Consortium (2021). Associations between HIV infection and clinical spectrum of COVID-19: a population level analysis based on US National COVID Cohort Collaborative (N3C) data. The lancet. HIV, 8(11), e690–e700. https://doi.org/10.1016/S2352-3018(21)00239-3

Yusuf, S., Joseph, P., Rangarajan, S., Islam, S., Mente, A., Hystad, P., Brauer, M., Kutty, V. R., Gupta, R., Wielgosz, A., AlHabib, K. F., Dans, A., Lopez-Jaramillo, P., Avezum, A., Lanas, F., Oguz, A., Kruger, I. M., Diaz, R., Yusoff, K., Mony, P., & Dagenais, G. (2020). Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study. Lancet (London, England), 395(10226), 795–808. https://doi.org/10.1016/S0140-6736(19)32008-2


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